When attempting to publish a Nintex Workflow, the workflow fails to publish and presents an error regarding Federal Information Processing Standards (FIPS).

This is a SharePoint limitation. According to Microsoft, SharePoint is not FIPS-compliant due to its use of encryption algorithms that do not comply with Federal Information Processing Standards. The non-compliant encryption algorithms are used for processing purposes (i.e. unique identifiers) and are not used for security.

 

To disable FIPS, please do the following on each SharePoint Server within your environment:

 

 

soap:ServerServer was unable to process request. ---> Failed to publish workflow: <Error><CompilerError Line="-1" Column="-1" Text="Compilation failed. This implementation is not part of the Windows Platform FIPS validated cryptographic algorithms." /></Error>

From Microsoft's Security and protection for SharePoint Server 2010:

"SharePoint Server 2010 uses several Windows encryption algorithms for computing hash values that do not comply with Federal Information Processing Standard (FIPS) . . . These algorithms are not used for security purposes; they are used for internal processing. For example, SharePoint Server 2010 uses MD5 to create hash values that are used as unique identifiers."
 

Security and protection for SharePoint Server 2010
https://docs.microsoft.com/en-us/previous-versions/office/sharepoint-server-2010/cc263215(v=office.14)?redirectedfrom=MSDN