Salesforce is migrating our instance. Are there any actions that need to be taken in regards to Drawloop to avoid any issues or disruptions?

If you have Mass via Report feature - Please reconfigure the remote site instance. This can be done in the DocGen Admin Setting Tab. Otherwise, there should not be any problems with moving to a different instance. 

The only time there would be a concern is if you have the instance parameters on your button(s), and they are hardcoded. Those would need to be updated to the new instance.

Other than the above-mentioned, our product should not be affected by the migration of the Salesforce Instance.