This blog gives a quick over view on Ports/Url's to consider when setting up Nintex Live in your corporate network. 

Reference Material:

• For how to enabled guidance please see the help file here Connect and enable Nintex Live 
• For complete architecture document please see this Overview of the Nintex Live service Nintex Live - Architecture Overview  

The Urls/Ports

Url's 

• https://live.nintex.com

• https://liveservices.nintex.com

• https://nintexlive.blob.core.windows.net/serviceicon

• https://nintexrelay.servicebus.windows.net

• https://cm.nintex.com (to connect to Connection Manager)

• https://run.nintex.io (to connect to the Start Workflow API for External Start)

• https://prdswasbuwus01.servicebus.windows.net (to connect to External Start)

Ports

• 9351

• 80

• 443

• 5671 (https://nintexrelay.servicebus.windows.net)
• 5672

There is a chance you will run into an IP address change. So if you look them up please be aware as they are dynamic.