Symptoms

Error on "Activate All K2 Features and K2 Configuration Settings" page on upgrade
 

Diagnoses

When doing an upgrade from 4.6.9 to 4.6.10 everything goes fine until configuration of the SharePoint components, where I get an error: "The selected SharePoint My Site collection is not supported"
 

Resolution

If you are running SP2013 please ignore the feature activation.
Due to changes in SP2013 architecture it does not use feature (.wsp) anymore and thus no K2 features needs to be deploy.