It is not possible to override the calendar object so that every time someone in salesforce clicks on a calendar link they go to the Skuid Page.  The Buttons and Link OVerrides are not exposed for that object.  (Maybe the Metadata API?). 

But you can totally build a skuid calendar for your salesforce events. 
And you can expose that calendar to your users within thier salesforce experience by: 

A: Creating a VF Tab that calls this skuid page directly.
B: Building a VF home page component that calls this skuid page directly.

You should be good to go.