Symptoms
Worklist item could not be opened. Unable to cast object of type 'System.String' to type 'SourceCode.Workflow.Client.User'.
I get the above error in v 4.7 which is documented in the following article even though it states that a fix had been released for version 4.6.
http://community.k2.com/t5/K2-blackpearl/Worklist-item-could-not-be-opened-Unable-to-cast-object-of-type/ta-p/77031
Diagnoses
We have done some investigation on our K2 Knowledge base and this related error is a known issue that is corrected in 4.7.
Resolution
Sent the client the code fix
Client successfully applied the code fix that resolved the issue.