Symptoms

A K2 My Process web part is throwing a HttpWebRequest_WebException_RemoteServer.
 

Diagnoses

Microsoft.NET Framework 3.5 does not support multiple bindings in IIS without configuring a single address and setting up a prefix filter as per the following MSDN KB (Refer to section ‘Multiple IIS Binding Support in .NET Framework 3.5’): http://msdn.microsoft.com/en-us/library/aa751841.aspx

 

Resolution

If the extra binding is required, follow the web.config changes detailed in the above Microsoft article.
"My processes" webpart is a silverlight report webpart. It uses WCF end points (e.g: /_vti_bin/SourceCode.ReportDataService/ReportDataService.svc)