Cannot Publish Workflow: SoapServerServer was unable to process request.

[Tjones]

My workflow Fails to Start.  I am not sure if its identical or closely related.

[Nevicar]

That's the identical behavior mine exhibits when attempting to manually start the workflow too. Cool. 

[Nevicar]

since the actual support here seems to be minimal from anyone "official", here's what seems to be the actual fix to the problem

https://support.microsoft.com/en-us/topic/some-scenarios-of-sharepoint-2010-workflow-are-affected-af...

good luck

[Tjones · Accepted solution]

I got feedback from Nintex and sharing it here.  Verified it does work.

Microsoft's July 2021 CU has an issue that affects the 2010 workflow engine.
As Nintex also uses this engine, Nintex workflows are affected.
Please see our knowledge Base article which has a solution and a link to the Microsoft blog explaining the issue.
https://community.nintex.com/t5/Technical-Issues/Unable-to-publish-or-run-workflows-after-installing...
If your issues persist please see the link to Microsoft's blog at the end of the article which contains a workaround for the issue they have caused.

[koen_reynaert]

Didn't worked for us. Had to follow the workaround of MS by setting $farm.EnablePreParseSecurityCheckForWorkflow to $false.