I am not sure if this will help but the following article explains how to go about associating and disassociating a K2 process with a SharePoint Library:
However, from what I know, you cannot remove SharePoint workflow integration from a process solution once it has been added due to how fundamental this is from a process design perspective.
Don’t think it is possible to remove any integration once it
has been added. You will have to start a new project to add the correct
integration. Don’t know the exact reason behind this though. what you can do is log a Support ticket to get this logged as a feature request.