In addition to this blog, you can search the Nintex for SharePoint 2016 help for "Nintex Workflow Exchange Connector Service."
The following Nintex Workflow action uses the Nintex Workflow Exchange Connector Service to communicate with Exchange (2007, 2010, and 2013):
Setting up your environment to use Exchange for Nintex Workflow actions involves installing the Nintex Workflow Exchange Connector Service, adding root certificates to SharePoint, and ensuring that the intended user has access to the target calendars.
The following errors may indicate the need to set up your environment to use Exchange.
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